Exploring The Intriguing Path Of Strep Bacteria Into The Brain
Expert Explains How Strep A Can Affect Children, Adults | Usa Today
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How Does Strep Get On The Brain?
How does streptococcus (strep) bacteria reach the brain?
Meningitis is a condition that arises when bacteria manage to breach the body’s natural defenses and access the brain. This can occur through several routes, including the bloodstream or direct contact between the protective membranes surrounding the brain, known as meninges, and external sources such as the skin or the nasal cavity. One common scenario involves the colonization of the nasopharynx by bacteria like Streptococcus pneumoniae, which can evade the host’s immune system. By April 10, 2023, understanding the mechanisms behind this process is crucial for medical research and treatment development.
How Does Strep Throat Turn Into Meningitis?
The process by which strep throat progresses to meningitis, referred to as invasive Group A Streptococcal disease (iGAS), is a relatively rare occurrence. Group A Streptococcus (GAS) bacteria, while typically responsible for strep throat, can, in some cases, lead to bacterial meningitis. This transformation happens when the GAS bacteria enter the bloodstream and migrate to the meninges, which are the protective membranes encasing the brain and spinal cord. Once in the meninges, these bacteria trigger inflammation and swelling. This chain of events poses a potential risk of bacterial meningitis development. This information was last updated on December 16, 2022.
Summary 28 How does strep get into the brain
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Group B streptococci (GBSs) are the leading cause of neonatal meningitis. GBSs enter the CNS by penetrating the blood-brain barrier (BBB), which consists of specialized human brain microvascular endothelial cells (hBMECs).Meningitis occurs when bacteria enter the bloodstream and then cross the blood-brain barrier or through direct contact of meninges with the skin or nasal cavity. The most frequent focus of the infection is the nasopharynx colonized by S. pneumoniae that evades the host immune system.This is known as invasive Group A Streptococcal disease (iGAS). Although uncommon, GAS can also cause bacterial meningitis. This occurs when the bacteria travel through the bloodstream to the meninges (the membranes which surround and protect the brain and spinal cord), causing inflammation and swelling.
Learn more about the topic How does strep get into the brain.
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- Understanding Group A streptococcus (GAS) – Meningitis Now
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- How Does Streptococcus pneumoniae Invade the Brain? – Cell Press
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